阴阳路

一 |     该端口的目标是提醒医生注意感染的迹象，减少住院，并收集重要的生理数据以改善病人的预后。    

North Korea's leader Kim Jong Un and US President Donald Trump cross south of the Military Demarcation Line, after Trump briefly stepped over to the northern side, in the Joint Security Area (JSA) of Panmunjom in the Demilitarized zone (DMZ) on June 30, 2019. Photo: VCG
Just hours before a military exercise between the US and South Korea due to get underway on Monday, US President Donald Trump announced that Washington would reduce military exercises with key regional ally Seoul, citing his positive relationship with the North Korean leader and South Korea's lack of assistance with Iran, CNN reported.
Chinese experts see Trump's sudden decision to scale back military drills with South Korea as a signal of his intention to ease tensions on the Korean Peninsula and possibly return to direct diplomacy with Pyongyang. However, they warned that a carrot-and-stick approach may not work with Pyongyang, which has already seen Washington renege on its commitments. If Trump sincerely seeks peace on the peninsula, returning to the negotiating table with a genuine willingness to engage should be the first step.
Writing on Truth Social on Sunday, Trump said "based on my very good relationship with Kim Jong Un, of North Korea, I am not happy with the fact that the United States has, long ago, agreed to participate in Joint Military Exercises with South Korea."
"These exercises are not only costly, with much of these costs paid for by the United States of America (as usual!), but send a signal that is totally inappropriate and hostile, to a Country that, as long as Donald J. Trump has been President, has been unthreatening and respectful," wrote the US president, noting that since it was too late to cancel the exercises entirely, he had asked Defense Secretary Pete Hegseth to "substantially reduce" US participation.
The 11-day exercise, known as Ulchi Freedom Shield, was expected to involve about 18,000 South Korean troops. According to the US military, South Korean and US forces planned to conduct live-fire drills to test precision-strike and maneuver capabilities under complex operational scenarios, as well as river-crossing operations and the deployment of pre-positioned military supplies, South Korea's Chosun Ilbo reported.
Trump also reiterated his request for South Korea to help with the US war against Iran. "While somewhat unrelated, I recently asked the President of South Korea if they would like to join us in the Denuclearization of the Islamic Republic of Iran, and they said, 'No thanks!'" Trump wrote.
At a press conference of China's Foreign Ministry on Monday, a reporter also raised Trump's claim that he would scale back joint military exercises with South Korea, citing the high cost of the drills and his good relationship with North Korean leader, and asked how China would support the resumption of dialogue between the US and North Korea. Chinese Foreign Ministry spokesperson Lin Jian responded, "we have noted the relevant reports. Maintaining peace and stability on the Korean Peninsula and advancing the political settlement of the Korean Peninsula issue serve the common interests of all parties."
South Korean media Yonhap News Agency reported that Trump's instruction came as the situation on the Korean Peninsula remained tense again. The media noted that Trump's move can be seen as a conciliatory gesture toward the North Korea, after the White House repeatedly affirmed that Trump remains open to dialogue with Pyongyang "without any preconditions."
Trump has long sought to ease tensions on the Korean Peninsula, but his first-term diplomatic efforts produced few substantive results. The decision to scale back military exercises with South Korea may therefore signal an intention to send goodwill and return to direct diplomacy with North Korea, an unfinished piece of business from his first term, Song Zhongping, another Chinese military affairs expert, told the Global Times.
Long-standing tensions between the US and North Korea are a major source of instability on the Korean Peninsula, Lü Chao, an expert on East Asian studies at the Liaoning Academy of Social Sciences, told the Global Times, noting that the fundamental way to address these tensions is for the two sides to return to the negotiating table and resolve their differences through peaceful dialogue, rather than escalating tensions through displays of military force.
On August 13, a spokesperson for the Foreign Ministry of the Democratic People's Republic of Korea responded to the scheduled military drills between South Korea and the US. The spokesperson said that "it is our consistent principle of ensuring security to respond to a new level of a threat with a new level of a deterrent. DPRK remains steadfast in its will to frustrate outsiders' hostile acts with the most powerful and overwhelming force and absolutely defend the supreme interests of the state security," according to official Korean Central News Agency (KCNA).
On Saturday, Trump shared a photo of himself with Kim Jong Un, the top leader of the DPRK on Truth Social, and wrote that he and the North Korean leader "get along GREAT!"
During Trump's first presidential term, he and Kim first met in Singapore in June 2018, marking the first-ever US-DPRK summit. They met again in Hanoi, Vietnam in February 2019, and later that June in the inter-Korean border village of Panmunjom, according to Xinhua News Agency. 
North Korea's past dealings with the US, particularly the breakdown of bilateral negotiations without substantial progress, have eroded Pyongyang's trust in Washington, Lü said.
Therefore, if Trump genuinely wants to leverage his relationship with the North Korean leader to address tensions on the Korean Peninsula, emphasizing their personal ties alone will not be enough. Washington will need to demonstrate genuine sincerity and back its words with concrete action, according to the expert. 
。NXgenPort是首席执行官兼联合创始人Cathy Skinner的心血结晶，20年前她的父亲因癌症去世后，她根据自己的经验提出了这个端口的想法。

二 | 他的诊断结果使Skinner走上了在肿瘤学领域工作的道路，并成为一名癌症运动专家。2016年，她与一名乳腺癌患者一起工作，并注意到她的病情比Skinner最后一次见到她时恶化了。这名患者去看医生，得知她为抗癌而服用的药物也在损害她的心脏。

三 | “当她告诉我这个故事时，我看到她胸前有一个植入药物的化疗口，我就想，我们怎么就不能早点知道药物正在损害她的心脏呢？”Skinner在采访中告诉TechCrunch。

四 | “我一直知道我有一个好主意，但我需要一个团队来围绕它进行建设。

五 | ”这时，NXgenPort公司的首席运营官Rosanne Welcher博士和首席技术官Mohamed Ali医学博士开始参与其中。2019年，Skinner在哈佛大学参加一个会议，坐在Welcher旁边吃午饭，两人开始讨论他们的专业。在Skinner发现Welcher是一位在癌症诊断和领导方面拥有25年工作经验的科学家后，她就分享了她对NXgenPort的想法。随后，Skinner和Welcher于2020年5月成立了公司，并向犹他州的一名律师提交了一份非临时专利。他们的律师曾聘请Ali为该专利绘制产品图纸，之后，Ali分享了他对该产品的兴趣，并以他在康复科学和心脏护理方面的专业知识加入了他们的团队。

六 | NXgenPort嵌入了微电子和电池。

七 | 该设备有光学传感器穿过导管。一旦端口被植入胸部，导管穿过病人的心脏，该设备就会捕捉到血细胞的图像，然后压缩数据并将其发送到云端，之后通过机器学习进行分析。

八 | Skinner指出，细胞是由它们的大小和组成来区分的，因此该公司已经训练了算法来计算不同的细胞，然后提供趋势，说明血细胞是以好的还是坏的方式变化。

九 | “随着化疗端口的植入，再加上我们嵌入了远程病人监测的技术，我们能够检测到红血球和白血球的变化，心输出量和生命体征，”Skinner说。“现在，如果一个专利需要确定他们是否有资格接受下一次化疗预约，他们必须开车去诊所，并接受血液测试。

十 | 如果他们的血细胞计数不正常，他们就不符合条件，必须开车回家。我们正在进行远程监控，并显示一段时间内的趋势，看看数据是否显示出感染的迹象，如果病人需要提前来输血，或者化疗需要重新安排时间。”NXgenPort仍处于获得美国食品和药物管理局批准的过程中，因此该公司还不能对人类进行测试。这家初创公司今年将进入动物测试阶段，并从猪开始。Skinner说，这家初创公司预计将在2025年底开始进行人体测试。

十一 | Skinner表示：“这是一件非常困难和雄心勃勃的事情，我们正在寻求通过采用实验室中用于计数细胞的光学传感器，将它们小型化，并让它们在血流中被激活。

十二 | 所以我们面临着一些重要的挑战，但与此同时，当我们完成这项工作时，它将完全改变癌症患者的监测方式。我们在2025年进入市场的时机将非常合适，因为Hospital at Home模式将更加成熟，我们将准备好进行整合。

十三 | ”在资金方面，这家初创公司在2022年3月完成了预种子轮融资，包括来自联合创始人的朋友和家人、mHUB加速器和Edward-Elmhurst Health Ventures的投资。NXgenPort正在进行400万美元的种子轮融资，但目前无法透露主要投资者。该公司的A轮投资，Skinner说将由1000万美元组成，将在2023年进行。

十四 | 至于该公司的商业模式，Skinner表示，这家初创公司将着眼于向端口制造商、制药商和虚拟诊所试验公司授权该技术。NXgenPort本身的价格将比标准端口高一点，后者的价格通常在270美元左右。

十五 | 除了硬件之外，这家初创公司还将为其软件提供订阅模式，为医生收集和分析结果。Skinner说，该软件的价格约为每月40或50美元，将支付给管理端口的医院。尽管这家初创公司目前专注于癌症，但Skinner说这家初创公司的目标是在未来变成一家拥有不同产品线的公司。这家初创公司认为，在透析、心脏护理和兽医护理方面，带有光学传感器的植入式设备可以收集病人的血液数量和心脏功能，这是个机会。